Comparison of Various Submucosal Injection Solutions for Maintaining Mucosal Elevation During Endoscopic Mucosal Resection

• DOI: 10.1055/s-2004-814517
• Publication Date: 2004-07-09T08:08:56Z
• Authors: M. Fujishiro; N. Yahagi; K. Kashimura; Y. Mizushima; M. Oka; S. Enomoto; N. Kakushima; K. Kobayashi; T. Hashimoto; M. Iguchi; Y. Shimizu; M. Ichinose; M. Omata
• Keywords: Submucosa; Endoscopic mucosal resection; Sodium hyaluronate; Perforation

Background and Study Aims: One of the major complications endoscopic mucosal resection (EMR) for gastrointestinal tumors is perforation, most effective way preventing perforation to elevate lesion sufficiently by injection fluid into submucosa. Materials Methods: In order compare lesion-lifting properties several different solutions, 1 ml each following solutions was injected submucosa resected porcine stomach: normal saline, 3.75 % NaCl, 20 dextrose water, 10 glycerin with 0.9 NaCl plus 5 fructose, two sodium hyaluronate (SH) solutions.