Omeprazole Versus Ranitidine as Adjunct Therapy to Endoscopic Injection in Actively Bleeding Ulcers: a Prospective and Randomized Study

• DOI: 10.1055/s-2007-1005698
• Publication Date: 2008-11-07T09:14:41Z
• Authors: C. Villanueva; J. Balanzó; X. Torras; S. Sáinz; G. Soriano; D. González; F. Vilardell
• Keywords: Peptic

Backround and Study Aims: Although high rates of initial hemostasis can be achieved with endoscopic injection therapy in actively bleeding ulcers, the incidence rebleeding is not negligible. Optimal conditions for clotting may require achieving deep sustained acid inhibition to avoid deleterious effect pepsin secretions on hemostatic process. The aim this study was assess whether omeprazole could improve efficacy ranitidine as an adjunct treatment rebleeding.