Synthesis of 4(5)-Acyl-2-aminoimidazoles and Vinylogues
Sonogashira coupling
Imidazole
Acyl group
Urocanic acid
DOI:
10.1055/s-2007-990870
Publication Date:
2007-11-26T14:14:02Z
AUTHORS (4)
ABSTRACT
A convenient protocol for the preparation of 4(5)-acyl-2-aminoimidazoles and vinylogues is disclosed employing a crystalline imidazole-derived iminophosphorane as coupling partner in Heck Sonogashira reactions. For first time, derivatives urocanic acid bearing free amino group 2′-position are described.
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