Synthesis of a bioactive nanomaterial in the ternary system SiO2-CaO-MgO doped with CuO: The effect of Ball milling on the particle size, morphology and bioactive behavior

• DOI: 10.1063/1.5091430
• Publication Date: 2019-02-27T01:32:25Z
• Authors: G. K. Pouroutzidou; G. S. Theodorou; E. Kontonasaki; L. Papadopoulou; N. Kantiranis; D. Patsiaoura; K. Chrissafis; C. B. Lioutas; K. M. Paraskevopo...
• Keywords: Nanomaterials; Bioactive Glass

Nanotechnology has a great potential to improve biomaterials used in tissue engineering. Nano-bioceramics are preferable compared their micro-scale counterparts, because of increased surface area, improving both mechanical properties and apatite-forming ability due the nucleation sites provided. Elements such as Si, Ca Mg for synthesis bioglasses have significant effect on bone metabolism, they particularly important regeneration this type glasses present high residual glassy phase, hardness values hydroxyapatite-forming ability. Cu, trace element human body, is known play role angiogenesis, which basic requirement new formation. The aim work was Sol-Gel derived nano-bioceramics quaternary system SiO2-CaO-MgO-CuO evaluation ball milling particle size, morphology bioactive behavior.