Steroid hormone concentrations and body mass are differently affected by polyunsaturated fatty acids during the oestrous cycle in guinea pigs

• DOI: 10.1071/rd17242
• Publication Date: 2018-01-08T00:25:13Z
• Authors: Matthias Nemeth; Bernard Wallner; Carina Siutz; Elisabeth Pschernig; Karl-Heinz Wagner; Eva Millesi
• Keywords: Steroid hormone

Reproductive functions in female mammals can be significantly affected by the actions of dietary polyunsaturated fatty acids (PUFAs) on steroid hormone secretion rates. Nevertheless, effects plasma free PUFAs oestrous cycle have seldom been considered. Therefore, present study, diet domestic guinea pigs was supplemented with high concentrations different and altered PUFA patterns concentrations, measured non-invasively, body mass during oestrus dioestrus were analysed. The characterised increased oestrogen cortisol oestrus, corroborated lowest bodyweight, whereas progesterone highest dioestrus. Plasma long-chain docosahexaenoic acid (DHA; 22:6 ω3) arachidonic (AA; 20:5 ω6) differently DHA positively diminished only oestrus. In contrast, AA negatively stimulated reduced general. These findings imply selective opposite contributions to ovarian stages cycle, indicating a biological relevance reproductive function.