Molecular signatures of ribosomal evolution

• DOI: 10.1073/pnas.0804861105
• Publication Date: 2008-09-04T00:53:59Z
• Authors: Elijah Roberts; Anurag Sethi; Jonathan Montoya; Carl R. Woese; Zaida Luthey-Schu...
• Keywords: Ribosomal protein; 28S ribosomal RNA; 5S ribosomal RNA; 5.8S ribosomal RNA

Ribosomal signatures, idiosyncrasies in the ribosomal RNA (rRNA) and/or proteins, are characteristic of individual domains life. As such, insight into early evolution can be gained from a comparative analysis their respective signatures translational apparatus. In this work, we identify both sequence and structure rRNA analyze contributions to universal phylogenetic tree using sequence- structure-based methods. Domain-specific proteins considered own right. Although it is commonly assumed that they developed after present evidence at least one may have been before divergence organismal lineages. We find correlations between showing coevolved with domain-specific proteins. Finally, show genomic organization components contains these as well. From studies, propose remnants an evolutionary-phase transition occurred cell lineages began coalesce so should reflected corresponding throughout fabric its genome.