Identification of a cellulose synthase-associated protein required for cellulose biosynthesis

• DOI: 10.1073/pnas.1007092107
• Publication Date: 2010-07-02T02:55:26Z
• Authors: Ying Gu; Nick Kaplinsky; Martin Bringmann; Alex Cobb; Andrew Carroll; Arun Sampathkumar; Tobias I. Baskin; Staffan Persson; Chris R. Somerville
• Keywords: Repetitive Sequences, Amino Acid; 0301 basic medicine; cell walls; Arabidopsis Proteins; Recombinant Fusion Proteins; polysaccharides; Arabidopsis; Marine Biology; Hypocotyl; CESA complexes; microtubules; Protein Transport; 03 medical and health sciences; Glucosyltransferases; Microfibrils; Mutation; Carrier Proteins; Cellulose; Biology; cell expansion; Cell Proliferation

Cellulose synthase-interactive protein 1 (CSI1) was identified in a two-hybrid screen for proteins that interact with cellulose synthase (CESA) isoforms involved primary plant cell wall synthesis. CSI1 encodes 2,150-amino acid contains 10 predicted Armadillo repeats and C2 domain. Mutations cause defective elongation hypocotyls roots reduce content. is associated CESA complexes, csi1 mutants affect the distribution movement of complexes plasma membrane.