Neurobiological basis of head motion in brain imaging

• DOI: 10.1073/pnas.1317424111
• Publication Date: 2014-04-08T04:10:32Z
• Authors: Ling-Li Zeng; Danhong Wang; Michael D. Fox; Mert Sabuncu; Dewen Hu; Manling Ge; Randy L. Buckner; Hesheng Liu
• Keywords: Brain mapping; Motion analysis

Significance This study expands our understanding of head motion in brain imaging. Complementing the common knowledge that artifacts can distort connectivity measures by causing artifacts, this identifies a neurobiological trait is linked to differences motion. correlate consists reduced distant functional primarily default network areas individuals with high Importantly, stable within across time. These findings may revise interpretations imaging many neurodevelopmental, aging, and neuropsychiatric studies. In addition, differentiating true disease effects from correlates tendency as reported here critical for using markers clinical arena because reduce specificity biomarkers.