Genetic analysis of the metabolome exemplified using a rice population

• DOI: 10.1073/pnas.1319681110
• Publication Date: 2013-11-21T04:55:54Z
• Authors: Liang Gong; Wei Chen; Yanqiang Gao; Xianqing Liu; Hongyan Zhang; Caiguo Xu; Sibin Yu; Qifa Zhang; Jie Luo
• Keywords: Metabolome; Phenome; Trait; Candidate gene

Significance Although plant metabolites are critical for both and human nutrition, the genetic control of metabolome remains largely unknown. Here, a analysis rice resulted in identification hundreds metabolic quantitative trait loci with high resolution large effects. We observed distinct overlapping accumulation patterns complex regulation metabolism different tissues. Twenty-four candidate genes, mainly those underlying phenolics, were assigned corresponding pathways reconstructed rice. This study demonstrated powerful tool provided vast amount high-quality data understanding biochemical basis metabolome. It is also valuable crop improvement through metabolomics-assisted breeding.