AM(1), THE FIRST GENETIC MARKER OF HUMAN IMMUNOGLOBULIN A
Mendelian inheritance
Subclass
DOI:
10.1073/pnas.64.4.1211
Publication Date:
2006-05-31T06:17:31Z
AUTHORS (2)
ABSTRACT
The genetic markers of human immunoglobulins have significantly contributed to the understanding molecular biology antibody synthesis. Like Gm IgG, first marker serum IgA, a major immunoglubulin exocrine secretions, has now been defined and termed Am(1). It is inherited as Mendelian dominant trait independent Inv allotypes. Am(1) localized in alpha-chains gammaA(2) subclass levels. Its polymorphism makes it suitable for studies population genetics IgA globulin.
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