Ubiquitous, interspersed repeated sequences in mammalian genomes.

• DOI: 10.1073/pnas.77.3.1398
• Publication Date: 2006-05-31T08:11:35Z
• Authors: W R Jelinek; T P Toomey; L Leinwand; C H Duncan; P A Biro; P V Choudary; S M Weissman; C M Rubin; C M Houck; P L Deininger; C W Schmid
• Keywords: Repeated sequence; Sequence (biology)

DNA base sequence comparisons demonstrate that the principal family of 300-nucleotide interspersed human sequences, repetitive double-strand regions HeLa cell heterogeneous nuclear RNA, and specific RNA polymerase III in vitro transcripts cloned sequences are all representatives a closely related sequences. A segment approximately 30 residues these is highly conserved mammalian evolution because it also present repeated Chinese hamsters. Further portion this mamalian similar to found within low molecular weight hydrogen-bonds poly(A)-terminated molecules hamsters forms half perfect inverted repeat near origin replication papovaviruses.