NewDrosophilaintrons originate by duplication

• DOI: 10.1073/pnas.95.4.1658
• Publication Date: 2002-07-26T14:40:11Z
• Authors: Rosa Tarrío; Francisco Rodrígu...; Francisco J. Ayala
• Keywords: 0301 basic medicine; Base Sequence; Xanthine Dehydrogenase; Diptera; Molecular Sequence Data; Biological Evolution; Introns; 03 medical and health sciences; Species Specificity; Multigene Family; Genetics; Animals; Drosophila; Amino Acid Sequence; Sequence Alignment; Phylogeny

We have analyzed the phylogenetic distribution of introns in gene coding for xanthine dehydrogenase 37 species, including 31 dipterans sequenced by us. discovered three narrowly distributed novel introns, one medfly Ceratitis capitata , second willistoni and saltans groups Drosophila third two sibling species group. The these favors “introns-late” theory origin genes. Analysis nucleotide sequences indicates that all arisen duplication a preexisting intron, which is pervasive other (and has homologous position as an intron found humans diverse organisms).