Characterization of a High Capacity Calcium Transport System in Mitochondria of the Yeast Endomyces magnusii

• DOI: 10.1074/jbc.273.8.4372
• Publication Date: 2002-07-26T15:13:03Z
• Authors: Elena N. Bazhenova; Yulia I. Deryabina; Ove Eriksson; Renata A. Zvyagil...; Nils-Erik L. Saris
• Keywords: Characterization

The Ca²⁺ transport system of<i>Endomyces magnusii</i> mitochondria has been shown previously to be activated by spermine. Here we report it regulated also low, physiological ADP concentrations, the intramitochondrial NADH/NAD⁺ ratio, and ions. combination of all these modulators induced high initial rates uptake Ca²⁺-buffering capacity yeast mitochondria, enabling them lower medium [Ca²⁺] ∼0.2 μm. mechanisms stimulation agents are discussed.