Molecular epidemiology of infectious bursal disease virus in the Near East and Persian Gulf regions

• DOI: 10.1080/03079457.2023.2270531
• Publication Date: 2023-10-12T14:34:56Z
• Authors: Matteo Legnardi; Francesca Poletto; Safaa Alam; Abdallah Cherfane; Bertrand Le-Tallec; Giovanni Franzo; Claudia Maria Tuc...; Caterina Lupini; Daniela Pasotto; Mattia Cecchinato
• Keywords: Infectious bursal disease; Molecular Epidemiology

Infectious bursal disease virus (IBDV) is a ubiquitous immunosuppressive pathogen which severe burden to the poultry industry. Due frequent mutation and reassortment events, its double-stranded, bi-segmented RNA genome displays considerable heterogeneity, in turn produces profound differences antigenicity pathogenicity. In recent years, investigation of IBDV epidemiology has greatly benefited from proposal multiple phylogenetic classification systems prompted execution molecular surveys all over world, producing wealth standardized easily sharable data. The present epidemiological survey was conducted six Near East Persian Gulf countries characterize field IBDVs circulating region. Ninety-three broiler flocks, immunized with different vaccination protocols, were investigated one-year period by collecting eight individual samples at time. Using assays targeting both segments, belonging four genotypes detected 42 flocks across countries. While traditional very virulent (genotype A3B2) represented minority, atypical (A3B1, A4B1 A6B1) found circulate most Many strains related sequences other continents, supporting involvement Middle complex networks viral spreading. obtained results, combined available literature, allowed us update picture, hopefully favouring identification threats planning effective monitoring control strategies.