Value of modified qSOFA, glucose and lactate in predicting prognosis in children with sepsis in the PICU

• DOI: 10.1080/07853890.2024.2337714
• Publication Date: 2024-04-09T06:13:28Z
• Authors: Wanyu Jia; Xue Zhang; Ruiyang Sun; Peng Li; Daobin Wang; Xue Gu; Chunlan Song
• Keywords: Capillary refill

The purpose was to investigate how well age-adjusted modified quick Sequential Organ Failure Assessment (qSOFA) scores paired with blood glucose and lactate levels predict the outcomes of septicemic children in pediatric intensive care unit (PICU). One hundred who were diagnosed sepsis septic shock PICU Henan Children's Hospital eligible, other 20 patients same hospital at different times selected as a validation set. Respiratory rate (RR), heart (HR), capillary refill time (CRT), Alert, Voice, Pain, Unresponsive (AVPU) scale included qSOFA scoring criteria for scoring. primary outcome 28-day all-cause mortality. predictive values evaluated by ROC curve. In group, 50 male, female. mortality 52%. Fifty-one >1. serum level 2.4 mmol/L, 9.3 mmol/L. AUCs score, prediction 0.719, 0.719 0.737, respectively. cut-off one point, 3.8 mmol/L 10 AUC score set 0.925. When three indices combined, 0.817, Hosmer–Lemeshow goodness-of-fit test showed χ2 = 2.428 p .965. are admitted ICU, we recommend performing rapid bedside testing determine early prognosis.