Cell Surface Phenotypic Changes Induced in H9 T Cells Chronically Infected with HTLV Type I or HIV Type 1 or Coinfected with the Two Viruses

0301 basic medicine 0303 health sciences T-Lymphocytes Cell Membrane HIV Infections HTLV-I Infections Cell Line Immunophenotyping 3. Good health 03 medical and health sciences Antigens, CD HLA Antigens HIV-1 Humans Cell Adhesion Molecules
DOI: 10.1089/aid.1995.11.145 Publication Date: 2009-03-16T19:34:36Z
ABSTRACT
To investigate whether HTLV-I infection, HIV-1 or infection of HTLV-I-infected cells affect the expression cellular surface molecules, an T cell line derived from H9 was established (H36). uninfected infected with were then HIV-1. We have compared density different markers on these three lines. These consist cell-specific antigens (CD2, CD3, CD4, and CD8), activated (CD25 CD71), major histocompatibility complex (MHC) (class I II), adhesion molecules (LFA-1 ICAM-1). The experiments reported in this article show that chronic modulate several immunologically important antigens. nature extent lymphoid phenotypic modulation depend infecting virus. Furthermore, interact each other coinfected cells.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (51)
CITATIONS (21)