Approaches to Identifying Appropriate Medication Adherence Assessments for HIV Infected Individuals with Comorbid Bipolar Disorder

• DOI: 10.1089/apc.2011.0447
• Publication Date: 2012-06-11T16:13:59Z
• Authors: Jayraan Badiee; Patricia K. Riggs; Alexandra S. Rooney; Florin Vaida; Igor Grant; J. Hampton Atkinson; David J. Moore, a...
• Keywords: Medication Adherence

Assessing medication adherence in already difficult-to-treat HIV-infected subpopulations presents a unique challenge. The objective of this study was to compare different approaches assessing adherence: (1) electronic monitoring, (2) standardized self-report questionnaire, and (3) visual analogue scale, determine whether antiretroviral therapy (ART) measures differed for persons with bipolar disorder (HIV+ /BD+) as compared without /BD-). ART assessed 74 HIV-positive participants using the Medication Event Monitoring System (MEMS), AIDS Clinical Trials Group (ACTG) scale (VAS). Participants were classified adherent or nonadherent on each measure by previously validated cutscores. Correlations logistic regressions used examine associations between demographic clinical variables. In HIV+ /BD- group, significant correlations existed MEMS. Males comprised 81% population. averaged 44 years age 13 education. No found among /BD+ group. Among reporting either but based MEMS, 94% had diagnosis disorder. Bipolar predictor classification discordance measures. Our findings suggest that it remains difficult assess individuals Combined may be best way estimate adherence, provide basis interventions designed improve populations.