A Latent Class Analysis of Risk Factors for Acquiring HIV Among Men Who Have Sex with Men: Implications for Implementing Pre-Exposure Prophylaxis Programs

• DOI: 10.1089/apc.2015.0113
• Publication Date: 2015-09-21T10:48:10Z
• Authors: Philip A. Chan; Jennifer Rose; Justine Maher; Stacey Benben; Kristen Pfeiffer; Alexi Almonte; Joanna Poceta; Catherine E. Olde...; Sharon Parker; Brandon DL Marshall; Mickey Lally; Kenneth Mayer; Leandro Mena; Rupa Patel; Amy S. Nunn
• Keywords: Pre-exposure prophylaxis; Demographics; Anal sex

Current Centers for Disease Control and Prevention (CDC) guidelines prescribing pre-exposure prophylaxis (PrEP) to prevent HIV transmission are broad. In order better characterize groups who may benefit most from PrEP, we reviewed demographics, behaviors, clinical outcomes individuals presenting a publicly-funded sexually transmitted diseases (STD) clinic in Providence, Rhode Island, 2012 2014. Latent class analysis (LCA) was used identify subgroups of men have sex with (MSM) at highest risk contracting HIV. A total 1723 presented testing (75% male; 31% MSM). MSM were more likely test positive than heterosexual or women. Among 538 MSM, identified four latent classes. Class 1 had the rates incarceration (33%), forced (24%), but no infections. 2 <5 anal partners previous 12 months, lowest drug/alcohol use during lower prevalence (3%). 3 (7%) other STDs (16%), > 10 months (69%), anonymous (100%), (76%), prior (40%). 4 similar characteristics as 2. this population, PrEP include those >10 sexual per year, partners, STDs. LCA is useful tool identifying clusters that place higher infection practice.