IL-22/IL-22RA1 Promotes Human Tenon’s Capsule Fibroblasts Proliferation and Regulates Fibrosis Through STAT3 Signaling Pathway

• DOI: 10.1089/jop.2023.0122
• Publication Date: 2024-07-24T17:21:10Z
• Authors: Yang Zhao; Xinyue Zhang; Xiaoyu Zhou; Baihua Chen; Xuanchu Duan

Although it is now understood that most antiglaucoma surgeries fail because of scarring the filtering tract, underlying mechanism remains to be elucidated. The present study investigated by which interleukin (IL)-22/IL-22 receptor alpha 1 (IL-22RA1) signaling pathway regulates scar formation in glaucoma patients.