The Influence of Depression and Anxiety on Risk of Adult Onset Vulvodynia

• DOI: 10.1089/jwh.2010.2661
• Publication Date: 2011-08-08T16:54:17Z
• Authors: Maheruh Khandker; Sonya S. Brady; Allison F. Vitonis; Richard F. MacLehose; Elizabeth G. Stewart; Bernard L. Harlow
• Keywords: Vulvodynia; Depression

Studies have shown that women with vulvodynia are more psychologically distressed than without vulvodynia. These studies, however, not effectively established temporal associations between diagnosed psychiatric disorders and vulvodynia.The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) was administered to 240 case-control pairs of Interviews age at first onset mood anxiety disorder. Age information used determine whether the episode and/or antecedent or subsequent symptoms. Conditional logistic regressions tested depression likely among Cox proportional hazards modeling then estimate risk new recurrent disorder.After adjusting education, race, menarche, tampon use, sexual intercourse, odds were four-times compared (95% confidence interval [CI] 2.1-7.5). Vulvodynia associated disorder after adjustment (hazard ratio [HR] 1.7, 95% CI 1.1-2.6) did significantly change including history before reference controls in models.This is community-based epidemiologic study demonstrating DSM-IV-diagnosed influence increases both psychopathology.