Seroprevalence of Crimean Congo Hemorrhagic Fever Virus in Ijara District, Kenya

• DOI: 10.1089/vbz.2011.0914
• Publication Date: 2012-08-27T15:55:59Z
• Authors: Olivia Wesula Lwande; Zephania Irura; Caroline Tigoi; Edith Chepkorir; Benedict Orindi; Lillian Musila; Marietjie Venter; Anne Fischer; Rosemary Sang
• Keywords: Seroprevalence; Crimean–Congo hemorrhagic fever; Tick-borne disease

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease mainly affecting pastoralists who come in contact with animals infested Hyalomma ticks, which are the key vectors of CCHF virus (CCHFV). CCHFV has been detected among these ticks parts North Eastern Kenya. This study aimed to identify acute cases CCHF, and determine extent previous exposure an outpatient population attending Sangailu Ijara health centers, District, Kenya, presenting febrile illnesses. A total 517 human serum samples were collected from patients. The screened for presence IgM IgG antibodies using CCCHF-IgG ELISA test kits. multivariable logistic regression model was used investigate risk factors associated evidence CCHFV. single patient tested positive anti-CCHF IgM, while 96 IgG. seroprevalence 23% 14% Ijara. Most exposed persons aged 40–49 years. likelihood highest farmers (29%). Age, location, donkeys significantly Acute infections could be occurring without being this population. confirms identifies several significant