Genetic Network Analyzer: qualitative simulation of genetic regulatory networks

• DOI: 10.1093/bioinformatics/btf851
• Publication Date: 2003-02-12T19:58:00Z
• Authors: Hidde de Jong; Johannes Geiselmann; Céline Hernandez; Michel Page
• Keywords: Gene regulatory network

Abstract Motivation: The study of genetic regulatory networks has received a major impetus from the recent development experimental techniques allowing measurement patterns gene expression in massively parallel way. This progress calls for appropriate computer tools modeling and simulation regulation processes. Results: We present Genetic Network Analyzer (GNA), tool networks. is based on qualitative method that employs coarse-grained models use GNA illustrated by case network genes interactions regulating initiation sporulation Bacillus subtilis. Availability: model are available at http://www-helix.inrialpes.fr/gna Contact: [e-mail] * To whom correspondence should be addressed.