Bellerophon: a program to detect chimeric sequences in multiple sequence alignments

• DOI: 10.1093/bioinformatics/bth226
• Publication Date: 2004-04-13T00:34:51Z
• Authors: Thomas Huber; Geoffrey Faulkner; Philip Hugenholtz
• Keywords: 0301 basic medicine; rRNA gene chimeras; Statistics & Probability; Amplification; 250502 Physical Chemistry of Macromolecules; Gene; Polymerase Chain Reaction; Biochemical Research Methods; chimeric sequences; Evolution, Molecular; User-Computer Interface; 03 medical and health sciences; Sequence Analysis, Protein; Protein Isoforms; Interdisciplinary Applications; 250699 Theoretical and Computational Chemistry not elsewhere classified; Conserved Sequence; Phylogeny; 250503 Characterisation of Macromolecules; Internet; Sequence Homology, Amino Acid; Chimera; Proteins; multiple sequence datasets; 280302 Software Engineering; Pcr; Biotechnology & Applied Microbiology; Computer Science; Sequence Alignment; Mathematics; Algorithms; Software; Bellerophon

Abstract Summary: Bellerophon is a program for detecting chimeric sequences in multiple sequence datasets by an adaption of partial treeing analysis. Bellerophon was specifically developed to detect 16S rRNA gene chimeras in PCR-clone libraries of environmental samples but can be applied to other nucleotide sequence alignments. Availability: Bellerophon is available as an interactive web server at http://foo.maths.uq.edu.au/~huber/bellerophon.pl