ANCHOR: web server for predicting protein binding regions in disordered proteins

• DOI: 10.1093/bioinformatics/btp518
• Publication Date: 2009-08-29T01:11:16Z
• Authors: Zsuzsanna Dosztányi; Bálint Mészáros; István Simon
• Keywords: 0301 basic medicine; Internet; 0303 health sciences; Binding Sites; Protein Conformation; Computational Biology; Proteins; 3. Good health; Applications Note; 03 medical and health sciences; Sequence Analysis, Protein; Amino Acid Sequence; Databases, Protein; Software

Abstract Summary: ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding. The server incorporates the result of a general disorder prediction method, IUPred and can carry out simple motif searches as well. Availability: The web server is available at http://anchor.enzim.hu. The program package is freely available for academic users. Contact: [e-mail]