InCroMAP: integrated analysis of cross-platform microarray and pathway data

• DOI: 10.1093/bioinformatics/bts709
• Publication Date: 2012-12-21T07:29:49Z
• Authors: Clemens Wrzodek; Johannes Eichner; Finja Büchel; Andreas Zell
• Keywords: Microarray databases; Gene chip analysis

Abstract Summary: Microarrays are commonly used to detect changes in gene expression between different biological samples. For this purpose, many analysis tools have been developed that offer visualization, statistical and more sophisticated methods. Most of these designed specifically for messenger RNA microarrays. However, today, microarray platforms available. Changes DNA methylation, microRNA or even protein phosphorylation states can be detected with specialized arrays. technologies, the number available is small compared mRNA tools. Especially, a joint on same set samples hardly supported by most Here, we present InCroMAP, tool visualization high-level data from individual multiple platforms. Currently, InCroMAP supports mRNA, microRNA, methylation modification datasets. Several methods offered allow an integrated those The features range over annotation targets enrichment all context metabolic signalling pathways. Availability: freely as Java™ application at www.cogsys.cs.uni-tuebingen.de/software/InCroMAP, including comprehensive user’s guide example files. Contact: [e-mail] [e-mail]