LPmerge: an R package for merging genetic maps by linear programming

Linkage (software)
DOI: 10.1093/bioinformatics/btu091 Publication Date: 2014-02-15T02:04:22Z
ABSTRACT
Abstract Summary: Consensus genetic maps constructed from multiple populations are an important resource for both basic and applied research, including genome-wide association analysis, genome sequence assembly studies of evolution. The LPmerge software uses linear programming to efficiently minimize the mean absolute error between consensus map linkage each population. This minimization is performed subject inequality constraints that ensure ordering markers in preserved. When marker order inconsistent maps, a minimum set ordinal deleted resolve conflicts. Availability implementation: on CRAN at http://cran.r-project.org/web/packages/LPmerge. Contact: endelman@wisc.edu Supplementary information: data available Bioinformatics online.
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