RNASeqMetaDB: a database and web server for navigating metadata of publicly available mouse RNA-Seq datasets

• DOI: 10.1093/bioinformatics/btv503
• Publication Date: 2015-09-01T00:34:13Z
• Authors: Zhengyu Guo; Boriana Tzvetkova; Jennifer M. Bassik; Tara Bodziak; Brianna M. Wojnar; Wei Qiao; Md A. Obaida; Sacha B. Nelson; Bo Hua Hu; Peng Yu
• Keywords: Gene Annotation

Abstract Summary: Gene targeting is a protocol for introducing mutation to specific gene in an organism. Because of the importance vivo assessment function and modeling human diseases, this technique has been widely adopted generate large number mutant mouse models. Due recent breakthroughs high-throughput sequencing technologies, RNA-Seq experiments have performed on many these models, leading hundreds publicly available datasets. To facilitate reuse datasets, we collected associated metadata organized them database called RNASeqMetaDB. The were manually curated ensure annotation consistency. We developed web server allow easy navigation data querying. Users can search using multiple parameters like genes, tissue types, keywords publications order find datasets that match their interests. Summary statistics are also presented showing interesting global patterns studies. Availability implementation: Freely at http://rnaseqmetadb.ece.tamu.edu. Contact: [e-mail]