Cas-analyzer: an online tool for assessing genome editing results using NGS data

• DOI: 10.1093/bioinformatics/btw561
• Publication Date: 2016-08-25T02:49:07Z
• Authors: Jeongbin Park; Kayeong Lim; Jin-Soo Kim; Sangsu Bae
• Keywords: Upload

Genome editing with programmable nucleases has been widely adopted in research and medicine. Next generation sequencing (NGS) platforms are now used for measuring the frequencies of mutations induced by CRISPR-Cas9 other nucleases. Here, we present an online tool, Cas-Analyzer, a JavaScript-based implementation NGS data analysis. Because Cas-Analyzer is completely at client-side web browser on-the-fly, there no need to upload very large datasets server, time-consuming step genome Currently, supports various nucleases, including single paired nucleases.Free access http://www.rgenome.net/cas-analyzer/ CONTACT: [e-mail] or [e-mail] information: Supplementary available Bioinformatics online.