LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering

• DOI: 10.1093/bioinformatics/btw729
• Publication Date: 2016-11-16T20:05:49Z
• Authors: Alicia T Specht; Jun Li
• Keywords: Expression (computer science)

Abstract Summary To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of cells to find that involves time delay. Availability and Implementation R package LEAP available CRAN Supplementary information data are at Bioinformatics online.