A nosographic analysis of the migraine aura in a general population

• DOI: 10.1093/brain/119.2.355
• Publication Date: 2007-01-13T16:54:21Z
• Authors: Michael Bjørn Rus...; Jes Olesen
• Keywords: Adult; Male; 03 medical and health sciences; 0302 clinical medicine; Migraine Disorders; Visual Perception; Humans; Female; 3. Good health

The study presented here is the first detailed nosographic analysis of migraine aura, diagnosed using criteria International Headache Society, in a sufficiently large sample for statistical analysis. Of 4,000 people, 163 had with aura. Sixty-two attacks aura headache as well without headache, and seven exclusively headache. Visual symptoms were most frequent (99%), followed by sensory (31%), aphasic (18%) motor (6%) symptoms. Those several types visual virtually every attack, while sensory, present only small number their attacks. typical starts flickering, uncoloured, zig-zag line centre field affect central vision. It gradually progresses towards periphery one hemifield often leaves scotoma. unilateral, hand, arm then affects face tongue. half-sided hand arm. visual, auras rarely lasted > 1 h, did 67% (six out nine). Four people acute onset duration characteristics ensuing suggesting that real phenomenon. 93%, occurred simultaneously 4% 3%. characteristic spread each symptom sequence different suggest cortical spreading depression mechanism underlying Our results do not alterations diagnostic Society are needed. intra-individual variation shown this indicates simplification Classification Diseases, Neurological Adaptation appropriate.