Stereoelectroencephalography in presurgical assessment of MRI-negative epilepsy

• DOI: 10.1093/brain/awm218
• Publication Date: 2007-09-14T00:17:52Z
• Authors: A. McGonigal; F. Bartolomei; J. Regis; M. Guye; M. Gavaret; A. T.-D. Fonseca; H. Dufour; D. Figarella-Branger; N. Girard; J.-C. Peragut; P. Chauvel
• Keywords: Stereoelectroencephalography

According to most existing literature, the absence of an MRI lesion is generally associated with poorer prognosis in resective epilepsy surgery. Delineation epileptogenic zone (EZ) by intracranial recording usually required but perceived be more difficult 'MRI negative' cases. Most previous studies have used subdural and there relatively less published data on stereoelectroencephalography (SEEG). The objective this study was report experience our group using SEEG presurgical evaluation, comparing its effectiveness normal lesional One hundred consecutive patients undergoing for assessment were studied. Forty-three out one (43%) had 57 (57%) MRI. Successful localization achieved no difference between these two groups, 41/43 (95%) 55/57 (96%) cases (P = 1.00). Surgery proposed 84/100 contraindicated 16/100 significant MRI-negative groups (P> 0.05). At 1 year follow-up, 11/20 (55%) those having undergone cortectomy 21/40 (53%) entirely seizure free 0.05) proportions maintained at 2 years follow-up. Significant improvement control (ILAE outcome 1–4) >90% Of that underwent surgery, 10/23 focal cortical dysplasia. This series showed equally effective evaluation epilepsies.