Successful treatment of urticarial vasculitis with omalizumab in children: a case series

• DOI: 10.1093/ced/llad192
• Publication Date: 2023-05-25T19:21:14Z
• Authors: Shan Wang; Libing Fu; Xin Xiang; Bin Zhang; Lin Ma; Huan Xing
• Keywords: Omalizumab; Tolerability

Urticarial vasculitis (UV) is a small vessel leucocytoclastic vasculitis, which often needs to be distinguished from urticaria and other dermatoses. Treatment of UV in children challenging because the unsatisfying efficacy antihistamines safety concern long-term systemic corticosteroids or immunosuppressive agents. As classic biological agent widely used chronic spontaneous urticaria, omalizumab might also potential therapeutic option treatment with UV. This report presented four children, aged 4-6 years, glucocorticoid-unresponsive successfully treated by omalizumab, thus providing evidence that can treat good tolerability paediatric population.