Can potentially infectious specimens containing hepatitis B virus be identified on the basis of their biochemical profile?

• DOI: 10.1093/clinchem/31.8.1329
• Publication Date: 2020-01-16T04:12:39Z
• Authors: L Burnett; S B Lowe; B Chan; J B Whitfield; B N Nightingale; W J Hensley
• Keywords: Infectivity

The potential infectivity of 1129 randomly selected plasma specimens was directly assayed by hepatitis B virus (HBV) DNA dot-hybridization. Presence or absence HBV then correlated with a biochemical profile 20 common analytes obtained on these same specimens. We found that potentially infectious could not be identified the basis any combination simple tests; indeed, were more "normal" in some tests liver function than non-infectious