HCSD: the human cancer secretome database

• DOI: 10.1093/database/bav051
• Publication Date: 2015-06-16T00:10:15Z
• Authors: Amir Feizi; Amir Banaei-Esfahani; Jens Nielsen
• Keywords: Human proteins

The human cancer secretome database (HCSD) is a comprehensive for data. describes proteins secreted by cells and structuring information about the will enable further analysis of how this related with tumor biology. from are believed to play deterministic role in progression therefore may be key find novel therapeutic targets biomarkers many cancers. Consequently, huge data on have been generated recent years lack coherent limiting ability query increasing community knowledge. We developed Human Cancer Secretome Database fulfil gap. HCSD contains >80 000 measurements 7000 nonredundant collected up 35 high-throughput studies 17 types. It has simple user friendly system basic advanced search based gene name , type as three main options. results visualized an explicit interactive manner. An example result page includes annotations, cross references, secretory features each identified protein.