Quantitative assessment of primary mitral regurgitation using left ventricular volumes: a three-dimensional transthoracic echocardiographic pilot study

• DOI: 10.1093/ehjci/jeu091
• Publication Date: 2014-05-23T06:38:26Z
• Authors: S. Marechaux; C. Le Goffic; P.-V. Ennezat; M. Semichon; A.-L. Castel; F. Delelis; J. M. Lemahieu; A. Menet; P. Graux; C. Tribouilloy
• Keywords: Stroke; Grading (engineering)

To investigate the value of assessment mitral regurgitant fraction (RF) using left ventricular (LV) volumes obtained by three-dimensional echocardiography (3DE) to quantify primary regurgitation (MR).Sixty patients with MR in sinus rhythm were prospectively enrolled. RF was calculated either 2DE or 3DE LV as follows: (LV total stroke volume - forward Doppler)/LV volume. Severity graded independently two cardiologists blinded volumetric data an integrative approach, recommended current guidelines. Sixty ejection >50% and no also studied. In without MR, 3D more strongly correlated than 2D (r = 0.75, P < 0.0001 vs. r 0.62, 0.0001, respectively). The method had a feasibility 90% MR. Inter-reader concordance for grading (four grades) excellent Kappa-value 0.90, 0.0001. A significant correlation observed between grade severity 0.83, 0.0001) 0.74, 0.0001). Comparisons individual grades (P 0.05) except 3+ 4+ 0.213). All ≥40% ≥3+ those ≤30% 1+ 2+ 'grey' overlap zone 30 40%.RF can be routinely determined high is reliable identification Grade incorporation this parameter into currently multiparametric approach might helpful discriminate