One-year outcome of wide-area pulmonary vein isolation using the third-generation visually guided laser balloon

• DOI: 10.1093/europace/euae102.161
• Publication Date: 2024-05-24T12:17:50Z
• Authors: T Yamasaki; K Kakita; M Pak; T Hattori
• Keywords: Isolation

Abstract Background The third-generation laser balloon (LB3) is equipped with an ultra-compliant and a motor-driven generator, which contribute to durable gapless isolated lesion creation. However, the efficacy of wide-area pulmonary vein (PV) isolation (PVI) using LB3 remains be elucidated. Purpose This study aims investigate PVI LB3. Methods single-center retrospective study. Patients atrial fibrillation (AF) who underwent ablation during period from August 2021 June 2022 were enrolled. All PVs electrically only by After initial circular ablation, was inflated larger size at each PV, area extended. voltage maps left atrium obtained high-resolution mapping catheters evaluate areas (<0.1mV). Follow-up included 12-lead electrocardiogram, Holter monitoring, and/or pacemaker/implantable cardioverter-defibrillator interrogation. endpoint defined as freedom tachyarrhythmia (ATa) between months 3 12. Results Forty-four patients paroxysmal AF 34 persistent (mean arrhythmia duration 12.4 months, range 1–60 months) included. First pass achieved in 90.6% (280/309) PVs. total application time 24.1±6.4 minutes, delivered energy 15.3±3.2 kJ. left- right-sided PV antrum 14.2±1.8 19.5±1.1 cm², respectively. At end 12 follow-up, ATa 78.2% 78.0% AF, indicates free survival one year similar both groups (P=0.91). Conclusions Wide-area may lead favorable outcomes AF.Fluoroscopic endoscopic imageKaplan-Meier curves map