Obstructive sleep apnoea risk profile and the risk of recurrence of atrial fibrillation after catheter ablation

• DOI: 10.1093/europace/eun315
• Publication Date: 2008-11-14T01:14:05Z
• Authors: R.-B. Tang; J.-Z. Dong; X.-P. Liu; J.-P. Kang; S.-F. Ding; L. Wang; D.-Y. Long; R.-H. Yu; X.-H. Liu; S. Liu; C.-S. Ma
• Keywords: Male; China; Sleep Apnea, Obstructive; Incidence; Comorbidity; Middle Aged; Risk Assessment; 3. Good health; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Risk Factors; Atrial Fibrillation; Catheter Ablation; Secondary Prevention; Humans; Female

The aim of this study was to identify the impact of obstructive sleep apnoea (OSA) on recurrence after catheter ablation of paroxysmal atrial fibrillation (AF).One hundred and seventy-eight consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. The patients were divided into high risk (HR group) and low risk (LR group) for OSA group with Berlin questionnaire. Of the 178 patients, 104 (58.4%) were in the HR group and 74 (41.6%) were in the LR group. After a mean follow-up of 344 +/- 137 (91-572) days, 44 patients (24.7%) experienced recurrence, and the recurrence rate did not differ between the HR (25.0%) and LR groups (24.3%, P = 0.855). Cox analysis revealed that PV isolation was the only independent predictor of recurrence (hazard ratio 5.11, 95% confidence interval 1.42-18.47, P = 0.013). There was no significant difference in the incidence of complications between the HR and LR groups (2.9 vs. 1.9%, P = 0.729).The recurrence rate and incidence of complications did not differ in patients with different risk profiles for OSA. The presence of OSA should not lower the decision threshold to choose an ablative procedure in paroxysmal AF.