1.11-P20Intergenerational transmission of health disparities among Turkish-origin residents in Germany: role of maternal stress and stress biology during pregnancy. A study protocol

• DOI: 10.1093/eurpub/cky048.044
• Publication Date: 2018-04-17T10:59:34Z
• Authors: L Scholaske; D Lindner-Matthes; M Kurt; E Duman; C Sahbaz; J Spallek; S Entringer
• Keywords: Disadvantage; Longitudinal Study; Generation R

Background:Turkish-origin immigrants constitute one of the biggest migration groups in Germany where they exhibit higher levels social disadvantage when compared to majority population. Research has elucidated underlying mechanisms by which is biologically embedded impact health over lifespan. However, relatively little known about how its effects are transmitted across generations.

Aims study: To elucidate maternal status and socioeconomic on stress-related maternal-placental-foetal (MPF) biological processes gestation subsequent infant birth outcomes.

Methods: We conducting a longitudinal cohort study N = 450 child-mother dyads with serial measures through first year life. Our proposed population will include approximately equal numbers Turkish-origin women Germany, German Turkish living Turkey their offspring. Study visits conducted from second trimester pregnancy end life assess socio-economic migration-related information, psychological well-being, nutrition, medical risk variables, MPF stress biology markers blood saliva samples. Infant anthropometric measures, developmental outcomes assessed throughout life.

Analyses: test specific hypotheses regarding association between background, biology. furthermore quantify background- disadvantage-related child outcomes.

Discussion: This foetal programming disparities focus Germany. The significance this derives importance achieving better understanding that alter disease vulnerability minority disadvantaged populations.