Cohort Profile: The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa

• DOI: 10.1093/ije/dyr080
• Publication Date: 2011-05-18T21:40:25Z
• Authors: M. Egger; D. K. Ekouevi; C. Williams; R. E. Lyamuya; H. Mukumbi; P. Braitstein; T. Hartwell; C. Graber; B. H. Chi; A. Boulle; F. Dabis; K. Wools-Kaloustian
• Keywords: Adult; Male; Patient Dropouts; 610 Medicine & health; HIV Infections; Comorbidity; Health Services Accessibility; Cohort Studies; 03 medical and health sciences; 0302 clinical medicine; 360 Social problems & social services; Pregnancy; Residence Characteristics; Neoplasms; Humans; Africa South of the Sahara; Acquired Immunodeficiency Syndrome; 1. No poverty; Middle Aged; CD4 Lymphocyte Count; Diet; Malaria; 3. Good health; Anti-Retroviral Agents; Africa; Female

In response to the HIV/AIDS pandemic in sub-Saharan Africa African networks of IeDEA (International epidemiologic databases Evaluate AIDS) aim inform scale-up ART region through clinical and research. Funded by National Institutes Allergy Infectious Diseases (NIAID) objectives across four regions (West Central East Southern Africa) are similar cover all populations including pregnant women infants children adolescents adult patients. They can be summarized as follows: (1) To prove robust evaluation delivery adults with a focus on long-term program effectiveness outcomes; (2) describe temporal trends regimen durability tolerability examine monitoring strategies; (3) important comorbidities co-infections HIV infection malaria tuberculosis cancer; (4) pregnancy- HIV-related outcomes initiating during pregnancy exposed or utero; (5) develop apply novel statistical methods deal missing data loss follow-up competing risks time-dependent confounding; (6) establish procedures link cohort other at local national level. The present report provides an indicative summary some major research themes key findings well discussion program’s strengths weaknesses.