EQUAL CPA Score 2022: a tool to measure guideline adherence for chronic pulmonary aspergillosis

• DOI: 10.1093/jac/dkac378
• Publication Date: 2022-11-14T17:52:47Z
• Authors: Rosanne Sprute; Eva Van Braeckel; Holger Flick; Martin Hoenigl; Chris Kosmidis; Ritesh Agarwal; Jesper R Davidsen; Christian B Laursen; Oliver A Cornely; Danila Seidel
• Keywords: Guideline; Gold standard (test)

Chronic pulmonary aspergillosis (CPA) can complicate underlying diseases, and clinical management of CPA is challenging. Guidelines support clinicians but due to the complexity disease they be difficult adhere to.To map current guideline recommendations for into a scoring tool facilitate quantify adherence in practice.Recommendations diagnosis, treatment follow-up presented ESCMID/ERS/ECMM CPAnet guidance documents were assembled weighed on basis their strength recommendation level evidence.Twenty-seven identified, resulting total maximum EQUAL Score 51. For diagnostics (ScoreMax = 27), strong emphasis expert consultation, culture, direct microscopy, histopathology, serology imaging was reflected respective points, whereas molecular techniques susceptibility testing count score lesser extent.Ten 14), including antifungal therapy, therapeutic drug monitoring duration, identified. Surgery, where indicated, adds three points. refractory or intolerance first-line treatment, optimal second-line added another two points.During 10), response assessment via gave while culture points each ScoreMax.The intents used as comprehensive measuring adherence. If guidelines associated with outcome, this will assessed future studies.