Adjuvant Chemotherapy with Uracil–Tegafur for Pathological Stage III Rectal Cancer after Mesorectal Excision with Selective Lateral Pelvic Lymphadenectomy: A Multicenter Randomized Controlled Trial*

• DOI: 10.1093/jjco/hyl014
• Publication Date: 2006-05-05T00:20:10Z
• Authors: Takayuki Akasu; Yoshihiro Moriya; Yasuo Ohashi; Shigeaki Yoshida; Kuniaki Shirao; Susumu Kodaira
• Keywords: Tegafur; Adjuvant Chemotherapy; Lymphadenectomy

Background: Although adjuvant radiotherapy was proved to be effective for local control of rectal cancer even after standardized mesorectal excision, the role chemotherapy such surgery remains clarified. We aimed assess efficacy a combination uracil and tegafur pathological stage III treated by excision with selective lateral pelvic lymphadenectomy.