Clinical outcomes of helical tomotherapy for super-elderly patients with localized and locally advanced prostate cancer: comparison with patients under 80 years of age

• DOI: 10.1093/jrr/rrv040
• Publication Date: 2015-08-28T20:44:02Z
• Authors: Noriyuki Okonogi; Hiroyuki Katoh; Hidemasa Kawamura; Tomoaki Tamaki; Takuya Kaminuma; Kazutoshi Murata; Yu Ohkubo; Yosuke Takakusagi; Masahiro Onishi; Tetsuo Sekihara; Atsushi Okazaki; Takashi Nakano
• Keywords: Tomotherapy; Cumulative dose; Cumulative incidence

We investigated the clinical outcomes of helical tomotherapy in 23 patients aged ≥80 years with localized and locally advanced prostate cancer compared results data from 171 under 80 years. All received our hospital between September 2009 October 2012. The median follow-up periods were 35 months group 34 younger group. prescribed dose was 78 Gy 39 fractions (range, 72–78 Gy). 3-year overall survival biochemical relapse-free rates 92% 96% 99.4% 97.3% group, respectively. There no significant difference two groups rates. cumulative incidences late Grade 2 or higher rectal toxicity urinary 13% 4.8% 7.0% 1.2% incidence toxicity. No exhibited 4 toxicity, all improved conservative therapy. Helical super-elderly had good control without severe Definitive may be treatment choice for cancer, even those older than age.