The Role of RING Dimerization in the E3 Ubiquitin Ligase Activity of the TRIM5α Retroviral Restriction Factor

• DOI: 10.1096/fasebj.29.1_supplement.888.9
• Publication Date: 2021-06-21T19:43:09Z
• Authors: Dmitri Ivanov; Zinaida Yudina; Rory Johnson; Nikolaos Biris; Alexander Taylor; P Hart; Borries Demeler
• Keywords: 0301 basic medicine; 03 medical and health sciences; 6. Clean water; 3. Good health

Members of the tripartite motif (TRIM) protein family of RING E3 ubiquitin (Ub) ligases promote innate immunity responses by catalyzing synthesis of K63-linked polyubiquitin chains in a manner that...