P-004 PULSE PRESSURE AMPLIFICATION OVER UPPER ARM

• DOI: 10.1097/01.hjh.0000408111.99127.13
• Publication Date: 2011-11-19T09:23:52Z
• Authors: Hao-Min Cheng; Shih-Hsien Sung; Chao-Feng Liao; Ying-Hwa Chen; Po-Hsun Huang; Wen-Chung Yu; Yuan-Ta Shih; Chen-Huan Chen
• Keywords: Brachial artery; Pulse pressure

Objectives We decomposed the lower body and upper limb reflections from brachial PW to quantify their relative contributions aorta-to-brachial Pulse pressure amplification (PPA). Background PPA between central aorta artery is affected by wave both local limb. Methods High fidelity aortic right PWs were simultaneously recorded at baseline 3 minutes after sublingual nitroglycerin (NTG) administration, using a custom-made dual sensor catheter in 54 patients (66.2 ± 13.0 year; 45 men). Lower reflected (amplitude = Pb) was PW. Local P0) obtained subtraction of foot-aligned Aorta-to-brachial pulse velocity (abPWV) calculated PWs. Results 5.4 5.9 mmHg increased 10.9 6.1 NTG. Pb decreased 39.6 18.7 % P0 6.7 29.0 By forward multivariate linear regression analysis, total variance (r2 0.76) could be explained (54.9%), (33.0%), arterial compliance (5.7%), abPWV (3.4%), transit time (3.0%), whereas 0.53) (57.3%), (37.2%), heart rate (5.5%). Conclusions reflection contributes substantially PPA, an emerging mechanical biomarker cardiovascular risk.