Systemic Extrapancreatic Lesions Associated With Autoimmune Pancreatitis

• DOI: 10.1097/01.mpa.0000175178.85786.1d
• Publication Date: 2005-09-14T09:53:20Z
• Authors: Hirotaka Ohara; Takahiro Nakazawa; Hitoshi Sano; Tomoaki Ando; Tetsu Okamoto; Hiroki Takada; Kazuki Hayashi; Yasuhiro Kitajima; Haruhisa Nakao; Takashi Joh
• Keywords: Autoimmune Pancreatitis; Systemic scleroderma; Systemic administration

Autoimmune pancreatitis (AIP) is often associated with systemic extrapancreatic lesions. We studied 31 cases of AIP to clarify the diversity lesions and differences between without lesions.The clinical features courses were compared by age, sex, blood chemistry those In addition, we reviewed available literature on AIP.Seven had lesions, which diagnosed simultaneously AIP; however, 1 case presenting various was independently lesion. Patients needed maintenance steroid therapy for in 4 2 cases; ratio requiring significantly higher among (6/8) than (7/23). There no significant groups regard extent narrowing main pancreatic duct, enlargement pancreas. gamma-globulin, IgG, IgG4 levels patients without. The found Sjögren syndrome, ulcerative colitis, retroperitoneal fibrosis, sialadenitis, thyroiditis, idiopathic thrombocytopenic purpura.The results this study suggest that, when encountering a elevated gamma-globulins, IgG4, an effort should be made detect other abnormalities initiate administration.