Decreased renal function is a strong risk factor for cardiovascular death after renal transplantation1,2

• DOI: 10.1097/01.tp.0000061602.03327.e2
• Publication Date: 2003-12-02T11:40:18Z
• Authors: Herwig-Ulf Meier-...; Rajendra Baliga; Bruce Kaplan
• Keywords: Infections; Kidney; Kidney Transplantation; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Cardiovascular Diseases; Risk Factors; Creatinine; Humans; Transplantation, Homologous; Postoperative Period; Registries; Retrospective Studies

Chronic kidney disease is thought to be a potential risk factor for cardiovascular death. In renal-allograft recipients, the most significant cause of The purpose this study was investigate if renal function has role in determining death recipients.We analyzed 58,900 adult patients registered United States Renal Data System who received primary transplant between 1988 and 1998 had at least 1 year graft survival. endpoint from event beyond transplantation. Secondary endpoints were caused by infections malignancy-related deaths. Cox proportional-hazard models used estimate effect on death, infectious while correcting confounding variables, such as donor recipient age, gender, race, end-stage disease, length dialysis before transplantation, source delayed function, immunosuppressive regimen.Serum creatinine values after transplantation strongly associated with Above serum value 1.5 mg/dL, there progressive increase significantly higher when lost allograft included analysis. There an association worsening but no death.Serum incidence independent known factors.