Perineural Clonidine Does Not Prolong Levobupivacaine 0.5% After Sciatic Nerve Block Using the Labat Approach in Foot and Ankle Surgery

• DOI: 10.1097/aap.0b013e3182606168
• Publication Date: 2012-12-18T18:24:28Z
• Authors: Roxane Fournier; Alexandre Faust; Olivier Chassot; Zdravko Gamulin
• Keywords: Levobupivacaine; Foot (prosody)

<h3>Background</h3> There is controversy about the effectiveness of perineural clonidine used as an adjuvant to local anesthetics. This study investigated whether addition 150 μg 0.5% levobupivacaine for posterior sciatic nerve block would prolong duration analgesia. <h3>Methods</h3> double-blind, prospective trial compared analgesic characteristics 20 mL plain versus plus in a (Labat approach) foot and ankle surgery. Sixty patients were randomized allocated receive either alone or clonidine, find 30% prolongation analgesia with adjuvant, using same SD. The onset (time from completion administration first morphine request), hemodynamic changes during surgery, need rescue analgesia, technical neurologic complications assessed over 24-hour period. <h3>Results</h3> sensory (in minutes) was similar groups (10 [5–20] vs 10 [5–23] minutes, median [interquartile range], respectively), time request pain medication (1215 [920–1530] 1275 [1067–1360] respectively). However, statistically significantly more subjects group than experienced decrease 20% systolic arterial pressure (50% 28% patients, respectively; <i>P</i> &lt; 0.028). No noted 24 hours. <h3>Conclusions</h3> Addition gluteal (Labat) did not but had slight effect on pressure.