The Impact of Acute Herpes Zoster Pain and Discomfort on Functional Status and Quality of Life in Older Adults

• DOI: 10.1097/ajp.0b013e318065b6c9
• Publication Date: 2007-06-15T08:04:26Z
• Authors: Kenneth E. Schmader; Richard Sloane; Carl Pieper; Paul M. Coplan; Alexander Nikas; Patricia Saddier; Ivan S. F. Chan; Peter Choo; Myron J. Levin; Gary Johnson; Heather M. Williams; Michael N. Oxman
• Keywords: Male; Pain; Middle Aged; Herpes Zoster; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Socioeconomic Factors; Data Interpretation, Statistical; Surveys and Questionnaires; Acute Disease; Quality of Life; Humans; Female; Prospective Studies; Aged; Pain Measurement

To describe the interference of herpes zoster (HZ) pain and discomfort with activities daily living (ADLs) health-related quality life (HRQL) during acute rash phase, to quantify relationship between HZ impaired ADLs HRQL in older persons.Prospective, observational study 160 outpatients age > or =60 at 4 US sites who completed Zoster Brief Pain Inventory (ZBPI), Impact Questionnaire (ZIQ), McGill Questionnaire, EuroQol, SF-12 questionnaires on a predetermined schedule. Patients rated 0 10 scale for ADL items ZBPI ZIQ. Interference scores were averaged create summary measures (ZBPI ADLI) ZIQ (ZIQ ADLI). A composite score was used mixed-effects models analyses association ADLI first 35 days after onset.HZ interfered all but greatest enjoyment life, sleep, general activity, leisure activities, getting out house, shopping. For every 1.0 point increase intensity, there 0.69 0.53 interference, respectively, 2.81 point, 1.57 1.95 decrease physical, mental scales, respectively.Acute has significant negative impact functional status adults. The magnitude increases increasing intensity.