Temporal Trends in the Epidemiology of Severe Postoperative Sepsis after Elective Surgery

• DOI: 10.1097/aln.0b013e3181cea3d0
• Publication Date: 2010-03-17T05:54:34Z
• Authors: Brian T. Bateman; Ulrich Schmidt; Mitchell F. Berman; Edward A. Bittner
• Keywords: Elective surgery; Organ dysfunction

Multiple studies have used administrative datasets to examine the epidemiology of sepsis in general, but entity postoperative has been studied less intensively. Therefore, we undertook an analysis using Nationwide Inpatient Sample, largest in-patient dataset available United States.Elective admissions patients aged 18 yr or older with a length stay more than 3 days for any 1 20 most common elective operative procedures were extracted from years 1997-2006. Postoperative was defined appropriate International Classification Diseases, Ninth Revision, Clinical Modification codes; severe as along organ dysfunction. Logistic regression assess significance temporal trends after adjusting relevant demographic characteristics, procedure, and comorbid conditions.We identified 2,039,776 analysis. The rate increased 0.3% 1997 0.9% 2006. This trend persisted covariables-the adjusted odds ratio per year increase study period 1.12 (95% CI, 1.11-1.13; P < 0.001). in-hospital mortality declined 44.4% 34.0% 2006; this also adjustment 0.94 0.93-0.95; 0.001).During 10-yr that studied, there marked concomitant decrease sepsis.