Incisional Negative Pressure Wound Therapy After High-Risk Lower Extremity Fractures

• DOI: 10.1097/bot.0b013e318216b1e5
• Publication Date: 2011-07-29T06:51:26Z
• Authors: James P Stannard; David A Volgas; Gerald McGwin; Rena L Stewart; William Obremskey; Thomas Moore; Jeffrey O Anglen
• Keywords: Negative-pressure wound therapy; Wound dehiscence

To investigate negative pressure wound therapy (NPWT) to prevent dehiscence and infection after high-risk lower extremity trauma.Prospective randomized multicenter clinical trial.Four Level I trauma centers.Blunt patients with one of three fracture types (tibial plateau, pilon, calcaneus) requiring surgical stabilization.Incisional NPWT (Group B) was applied the closed incisions study arm this trial, whereas standard postoperative dressings A) were control patients.Acute chronic infection.Two hundred forty-nine 263 fractures have enrolled in 122 Group A (controls) 141 B (NPWT). There no difference between groups distribution calcaneus (39%), pilon (17%), or tibial plateau (44%) fractures. a total 23 infections 14 B, which represented significant favor (P = 0.049). The relative risk developing an 1.9 times higher than treated (95% confidence interval, 1.03-3.55).There been studies evaluating incisional as prophylactic treatment incisions. Our data demonstrate that there is decreased incidence when their closure. also strong trend for decreases acute NPWT. Based on our prospective should be considered wounds severe skeletal trauma.